2024 college football picks, Week 4 odds, spreads, bets from proven expert: This 3-leg parlay pays 6-1

The Georgia Tech Yellow Jackets started their season by beating Florida State in Ireland, and after posting wins over Georgia State and VMI but a loss against Syracuse, the Yellow Jackets will get another chance against the ACC’s top opponent on Saturday. No. 19 Louisville will host Georgia Tech on Saturday, and the latest Week 4 college football odds list the Cardinals as 10.5-point favorites. Can Brent Key’s team pull off another upset win, or will Louisville start its journey toward the ACC Championship Game and the College Football Playoff with a win?

Other notable Week 4 matchups on Saturday include Illinois vs. Nebraska (-7.5), USC vs. Michigan (+5.5), Utah vs. Oklahoma State (+2.5), and Tennessee vs. Oklahoma (+7). So how should you handle all of those marquee contests on the Week 4 college football schedule, and what other Week 4 college football lines should you target in your parlays this week? Before locking in any Week 4 college football picks, be sure to check out the top Week 4 college football expert picks, predictions, and best bets from Thomas Cassell.

A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting for more than 30 years — and winning. Over the past two college football seasons, Casale is 122-92-5 (57%) on his college football picks and 26-8 (76.4%) in bowl games — all publicly recorded. Anyone who has followed him has been way ahead of the game.

Now, he’s turned his focus to Week 4 college football odds and is sharing his top three best bets at SportsLine. If you add them together, you can expect a return of about 6-1. Get his top college football picks at SportsLine.

Top Week 4 College Football Expert Predictions

One of Casale’s top Week 4 college football picks: He’s backing LSU (-24.5) against UCLA on Saturday. Chip Kelly led the Bruins to 25 wins over the past three seasons, but he made the shocking decision to leave the program to become the Ohio State offensive coordinator right when UCLA was about to make the jump to the Big Ten.

Speaking of DeShaun Foster, who rushed for 3,049 yards and 39 touchdowns in four years with the Bruins. Foster was a UCLA assistant from 2017-2023, but he hasn’t been able to move on from where Kelly left off. UCLA is averaging just 6.7 yards per pass attempt and 3.6 yards per rush this season and they’ll have trouble keeping up with LSU’s offense on Saturday.

“UCLA is one of the worst Power 4 teams in the country this season,” Casale told SportsLine. “The Bruins were lucky to beat Hawaii 16-13 and then Indiana beat them 42-13 at home. That score would have been even worse if Indiana hadn’t committed 14 penalties.” See what other picks Casale likes at SportsLine.

How to make college football picks for Week 4

Casale’s also got two other college football picks he likes, including backing an overlooked team that “excels in the underdog role.” You can see his picks only at SportsLine.

What are the best bets for Week 4 of college football, and which underdog should you bet on? Visit SportsLine now to see Thomas Casale’s best college football bets, all from a proven college football handicapper who’s gone 26-8 in bowl games over the past two seasons, and learn more.

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